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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f942289e403d8f81e655e834fa72ffa85e80158432452a3cf2b9df84418d0fcb' 
  AND token = 'S8JGCLBrv5l7f+gAmjdP2h808z60IQmxCazhHTl2eyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}