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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7768ed2c371ecd4c950b0c622eb4927b20d82b83811dda04e69657c7a52108d4' 
  AND token = 'GO4/+Xid8Wd1SOIS3D4MZutACcbGw6p/LqqalRJ3uvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}