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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9895c2e131a579621adc8c7eb7b444b7f5e37bc26950127372e0134c565dadf' 
  AND token = 't8hge8iOPAJCFnPlzI+mUaAWdn74YkNwaQN2di6FIyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}