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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3750a80ee865a5372042c26fa1ded1f22416fc5e804aae636d86126ca04f20a' 
  AND token = '5mb6xYLbGSUzu9UNzn/MQw/RHChPGcoU84tQbhZ1S1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}