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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b61fe524b3f74f790d16fcad0d2237bb7108218f34aa6da5ca923ba8ba8fec4' 
  AND token = 'EUP6Vo9lQh6ukyHqRZLGNF0kx2z7JtoDkj2y0I/EOa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}