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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7475881fdac296c364729f7c7fc57f161357eaceb6e7b50d141d086ac1938fef' 
  AND token = 'cUFgWaaMLnbUWAWSUa8Qv9QjkT8OUEc9sXnHY4xeDK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}