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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a4b64339b938d89739c8855ffa180795cc278acc683e972a9eb8d0b9bbe2a9' 
  AND token = '9GVieTGevx0EIGO9+SSipaWnUCES89Namr0yAWchSC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}