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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c847fe0f52b612c6fdbc13507ff30e6f1ae4e92aab3ca56022f7322ce904f657' 
  AND token = 'gKIHGNPKJuLBqip0a6eCiKpqMnI5NO4gum0CUOKfvRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}