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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9a632a273ec27db15bfa5a1e83fe7127b7e79eef0f351cd453e480b217728be' 
  AND token = '+OoU3qPCBpPuM3NDdMUSXXx28Q5ZOqBo28Y71Ke8lFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}