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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87ccff61ff1010aaa1b840067149c08954b6b07ee7f63d99aacc6e15cdc61803' 
  AND token = 'FUgJILaX/vIVDjKOm/FcCqgOlLKgvvQoLvOpfPWiBqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}