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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ade174b56e5529323b2051bcf42a31d7ab0cdf30d5955a848810628077e6ae62' 
  AND token = 'nyuwOWNbOkTwlxzsqpPvtUxcM35J1R3MqF3AB1tBs1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}