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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a3612b6cf489b803775cc132b482b3dc18801d55bbdfc1e57ee45fdfa6acbe' 
  AND token = 'ZffzC386BeCRd1HcVOs6ni0Pyb4kMEJSo2F0QNBAAZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}