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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2770b89161266f7179661bb8d0ae10915cd0d2ad5e60f1bcac3678884bc03e1' 
  AND token = 'DYQOQimCdPwkvbk+SZGSk+HBWcCq+0nal/IbqltMm/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}