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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f6e1dd82a61b939acac1d4f04d1c109b4f48b418d03b2094615334e7b2d302c' 
  AND token = 'rPIuQoASoAiF5ekkqTs7fMezLlMBdwr2Kht6fQulSQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}