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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d244d999ff8d9813f920d96705d87d3f0ef627c08f695544b082ede957e7165' 
  AND token = 'Wz6lB5slkoxTQQNnF9JYYLOOGh6LZMm5yW5CO45AwIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}