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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a936c315f274b26e6434f72e28990c2c297bb4360d0b5c0446caad82b004199' 
  AND token = 'CmNE9cY6x/GHT+vcGzuVAsMny4saj+Q8glp1jRtEyM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}