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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a40c871b42b2a9fbaf2c85a712bcf23c66177a871964990a9aaba1be7a47a2f' 
  AND token = 'ykzDo3GCWYXKMFMbhi9VRqTcclLQk7RP1J6yC9Jua/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}