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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ad64effd3be2e9853ed6440707405a18f75e6080a80cdc27fe19cda7c8e295' 
  AND token = 'eWcC3v+OJB883fzwGY92DMOlZsMb3qFKTu5LhYv8uDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}