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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4220990e06027745dbf43d363d016503acd0411f9c35d4cce40987e4d6a0b72' 
  AND token = '+JSD01geNmT83UbZwXhlI6CM4Dil3iGVm6YBUmGxicE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}