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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf56d43609d68fc1a27ec1e83d7a2046cb3411357b001982f42c8b7fc17d49f9' 
  AND token = 'yMgfocI2f0A2xYGtwJjFBSBjA3MDlnsXlMAk9qdS+HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}