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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede06bea3c27b56e519bc65a6db8345f915a8f6aad753d519c9a0e8a12dc348c' 
  AND token = 'txc4FDLiCihK8Vp6HXSpcIarrUTF8MCaGiem9phhjDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}