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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141fdda257759ebacfbfd5462c1203bafa74e84ea676ddd0b4b4303642d1449c' 
  AND token = 'fkY1M7WCS9VxJiz91id+Zc/ZTIxMBq+W3UvDPA8TT+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}