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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fc686924ee31d83d7d3d4b2f1359738c749cb00476cb541c3574c16b0948353' 
  AND token = 'AKpHQVY3/6zjOsnlXDDx0k0qskSyYKttkmHFWPVxS9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}