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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '371a94751e94f8ed11ca993f23f8437c78bafc3619b6f307e6ede6d8770111f2' 
  AND token = 'yKyN5NOv5UQjKg4LxadlL4lMJ3nEB4exNGCsFLLOAgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}