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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141b08cf344bf6e197808a67c1483ab65655eef58f134297e2ad67a130941456' 
  AND token = '9hFCwm3Qm3/LAM54SHnk8sEkdrCjtRqUWrimi9IbhUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}