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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d6b4eaebfe3826951b0a680f4ee81ff8d5ba3cc378a7c53e5bb0620ccfbd53d' 
  AND token = '+9kD4NQdtavQY8Rh5KbpMFbyb9q40HMFgs+UDNA4BGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}