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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92af2116a1a82b6301d99c830108bf4a8d423206b13dd3ba7dd1e91ca966296a' 
  AND token = 'XEdj02v7yevx/qoTVyOPDY2xGxLqnbtJQcsrStd3yVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}