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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b402b8ffcf3e46ae8752c53c3646b46d9b59b6a69c1bfc09287f9f4eae0008' 
  AND token = '8L4rK/DmsgnMAfc2ilH1LT4VPn5bFzUatXl80iZd6uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}