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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d9be8638111fd3a2c611aa60f1ba824a2cc435285888bb782aa774a1e8b2b3' 
  AND token = 'bISSePLPGCWGlN/vdAwGcOF6KihqMy1eeoIeErz06ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}