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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b75c16bc3caec90ea281ae2e8e02bcfb9ca35cd6fa2ec1d2f34dfd944d2ef69e' 
  AND token = 'wQtOFRx/vasjFgx9c+3rgIyTmsBc7XhXgQFKTQVg7+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}