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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3cb8c9e42a08075756278c3ce466a8fdf6fdeb22f3d227b8c18199e6c8a39ca' 
  AND token = 'bX+19Les1PUIKGLRQC+64IL4zqtPRpcBghQdKDbtI1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}