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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6296325eb181cd2e6ea010adfd01cfd1bfe8500f121dfcef07aa62d0f23fb43c' 
  AND token = '6CaGTY+ubopxzuzhyGZ5FVjW4zXsRHCIxO4f43jml/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}