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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebe02d60677f5c407bc363dcdf2877a044cebec7c21df403743664e5017516cb' 
  AND token = 'Sq4KqDh6qkcTraB3TvJeU7H/+gqOT1xVTrmZ+HOQiyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}