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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533c2c56ac553d87e2d00d14671b73a6d53ddea63a4a35efd93eb3633efec65b' 
  AND token = 'UdTVpnLxCKQdldK31VOoSZ1TJ/rAh90irMQE71c25y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}