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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736e3159d8cc4daf44c4b504fe8c99628d2162af493df354e5cad8b035ceeab3' 
  AND token = 'nxSno1e5wOEzsAV8/GzRHevMgzYyMlWHomb0ji2GCt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}