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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550fea68fd86f2392c2e8aecae54d5be4c01d141ccdf5836d46ec9d44d7cd8b1' 
  AND token = 'uawPD+MH3GSs0RRpmJfFZc27gqpxcaxPq0u71jbaCMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}