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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c8360a595668166f389f2d1b4720f3961dff92a3783909521e52ee5901a3e0' 
  AND token = 'uRir/BMEqEYJkFySxmR1K+4UTpVxXSsf0kHwErLKdeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}