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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4409bb304e315319a9ee43d6c99b7a907cb8bfd5c56bd6f6e71845f5914bf1c' 
  AND token = 'a6KCjI/MJ73kLnNHMc/LDTBXwAFDjlbxytZm0JS2laA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}