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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb16f526615bb5a7825f80f57addc3ddb32d512e613c417c69f6d70d5729daf3' 
  AND token = 'MOURWif+DYcKx4oksiF/LVkPdOnWJWXZyH9QVRwxatg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}