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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb13c2ed71e890e46149788afbef205f9ab66df1b69fe0dbe5ca70691e74d96b' 
  AND token = 't50/mPsURBzw1/PVVRSTC/xK8uEoVgmGHaqoBemXs1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}