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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4543e0d8e35eb5e7b3e2a161a46290e5455e9cb7c5c801d0ed53b07d37d73660' 
  AND token = 'l/P/8moEzs3aoxE+8nbHv18d0alct+vDdfb6kEGfdDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}