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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2fabcff838e6c6f1233d0d8a849b5a25bccfdb3e6cfcdeff035f14e674e43b8' 
  AND token = 'XKJ4x5Xc7zL1/H/4ZMMvjBMucOkvx6vlVqb53TKYa9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}