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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '262721d6808c69e9bf07eb59156b0fb6fe54284d94216bded8dc851baab5e8d1' 
  AND token = 'c1WI1HwmTAqhTvCwEngFk85Nx8ck8QBJt9LLilGrlps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}