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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c61d5eee4dca3262c4a86519556577688fb2a45e510e971af2a7e2ddc19c56f' 
  AND token = '2x/secFexRffP4cKpPW0w5DxBo57aO5KldVgdqxRMSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}