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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a76c1ea278830a0b85a604f2315f5b7d90fed3e3ada569606839fb64c783a635' 
  AND token = 'xB4S2QDLpF2BwK0WLHuwA8E5pLx4H7FY+2pdVByPba8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}