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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '598244f1c6aeafb89d5128908c8366d7cf6c5830562806a89b2c54d4f7234bf3' 
  AND token = 'KV9MEVdElpUoiVB4ZyeHAybUfWnqz3sdqW0ngSKw6pM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}