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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57009b2b67c8e9015c0eff2095d7c082e83fec307700de9e9393337029adc0d5' 
  AND token = 'e3MRQp1k4XanCnf+dArvaHNdTVrzLaG0ruFrYvrJ2qU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}