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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d54452eefbe9bf32fee5f6c7c11eea11e63c5ee942d8064c4a61b3dcf81e09d' 
  AND token = 'PiMzkn1JN6AC76DH5JAElelPKF9SIs02lklWXCiiC1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}