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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8601864dd0db2008607b9b503c671e8ed66a14ee3559c91783cace954c7a8b4f' 
  AND token = 'QrCwD2c/Ytd/B3Fnk/IfAqe8gFzdbdBqErNavSLGPjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}