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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '038eb26dd13a68cdc835f982d9120ca2db734e38ff791e72e2c1f4e4901b8318' 
  AND token = 'ILHD8NYOfEvtUDvEh2ymdiqtL7qhXH+bt7hW4W1gGwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}